How does one go about making a giant Chihuahua??Mess with the Igf-1 gene, which was recently discovered to play a role dictating the size of a dog. This may be a gene involved in making a type of growth factor.
There is actually something to be said for this research: dog breeds (purebreds at least) have less genetic variation than humans, and a very well documented breeding history. Therefore they make a great model for genetic hunts for, say, cancer-causing genes.
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